2019
- Preparation of heterocyclyl urea derivatives as modulators of tryptophan catabolism useful in treatment of diseases WO2019229464 More
- Preparation of substituted sulfonyl azacycles as modulators of hedgehog (Hh) signalling pathway WO2019043372 More
- Preparation of substituted cyclyl-sulfonamides as modulators of hedgehog (Hh) signalling pathway WO2019043373 More
- Preparation of pyrrolopyrimidine and pyrrolopyridine derivatives as ASK1 inhibitors WO2019012284 More
- Preparation of heterocyclyl urea derivatives as modulators of tryptophan catabolism useful in treatment of diseases WO2019229464 More
2018
- Modulators of Hedgehog (Hh) signalling pathway WO2018078360 More
2017
- Preparation of seco macrolide aminoglycosides for use in the treatment of prophylaxis More
2011
- New 14 and 15 membered macrolides for the treatment of neutrophil dominated inflammatory diseases WO2011131749 More
2010
- Tricyclic azabicyclo [4.1.0] heptane derivatives as inhibitors of serotonin, dopamine and norepinephrine re-uptake WO2010146025 More
- Anti-inflammatory macrolide WO2010086349 More
- 9-Deoxo- 9a-methyl- 9a- aza- 9a-homoerythromycin a derivatives for the treatment of neutrophil dominated inflammatory diseases WO2010086350 More
- 3′-N-substituted 9-deoxo-9a-methyl-9a-aza-homoerythromycin having antimalarial activity WO2010086351 More
2009
- Spiro compounds useful as antagonists of the H1 receptor and their stereoselective preparation, pharmaceutical compositions and use in the treatment of sleep disorders WO2009016084 More
- 9-Deoxo-9a-methyl-9a-aza-9a-homoerythromycin a derivatives and their use for the treatment of malaria WO2009016142 More
- 2′-O, 3′ -N-bridged macrolides WO2009130189 More
2007
2006
- Use of immune cell specific conjugates for treatment of inflammatory diseases of gastrointestinal tract WO2006018698 More
- Novel antimalarial 9a-carbamoyl-aminoalkyl and 9a-thiocarbamoyl-aminoalkyl azalides WO2006085228 More
- Monoamine reuptake inhibitors for treatment of cns diseases and disorders WO2006109190 More
- Macrolones – amino substituted quinolones WO2006050942 More
- Macrolones WO2007054296 More
- Macrolone compounds WO2006050943 More
- Macrolides with anti-inflammatory activity WO2006087644 More
- Macrolide compounds containing biotin and photo-affinity group for macrolide target identification WO2006106440 More
- Ether linked macrolides useful for the treatment of microbial infections WO2006120541 More
- Decladinosyl macrolides with anti-inflammatory activity WO2006077501 More
- Conjugates with anti-inflammatory activity WO2006046123 More
- Bis-(coumarin) compounds with anti-inflammatory activity WO2006111858 More
- Anti-inflammatory macrolide conjugates WO2006075255 More
- Anti-inflammatory conjugates of macrolides and coumarins WO2006092739 More
- 9a-Carbamoyl and thiocarbamoyl azalides with antimalarial activity WO2006087642 More
- 9a-carbamoyl and thiocarbamoyl azalides with anti-inflammatory activity WO2006097849 More
- 9a-Carbamoil-γ-aminopropyl- and 9a-thiocarbamoyl-γ-aminopropyl-azalides with antimalarial activity WO2006075256 More
- 4″ Amino linked macrolides useful for the treatment of microbial infections WO2006120545 More
2005
- Use of benzonaphthoazulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005072728 More
- Use of 3-aza-1-oxa-dibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005049036 More
- Use of 2-thiadibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005041856 More
- Use of 1-thia-3-aza-dibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorder WO2005049020 More
- Use of 1-oxa-dibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005049010 More
- Use of 1-aza-dibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005049011 More
- Use of 1,3-diaza-dibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005049016 More
- Use of 1,2-diaza-dibenzo[e,h]azulenes for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005049015 More
- Supstituted furochromene compounds, their preparation and antiinflammatory activity WO2005010007 More
- Substituted furochromene compounds of antiinflammatory action WO2005010006 More
- Solid state forms of (-)-(1R,2S)-2-amino-4-methylene-cyclopentanecarboxylic acid WO2005100302 More
- Preparation of 1-aza-2-oxa-dibenzo[e,h]azulenes and their use for the manufacture of pharmaceutical formulations for the treatment and prevention of central nervous system diseases and disorders WO2005049623 More
- Furochromen derivative with antiinflamatora effect WO2005095411 More
- Ester linked macrolides useful for the treatment of microbial infections WO2005108412 More
- Carbamate linked macrolides useful for the treatment of microbial infections WO2005108413 More
2004
- Substituted 9a-N-{N’-[4-(sulfonyl)phenylcarbamoyl]} derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-O-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A WO2004043985 More
- Substituted 9a-N-[N’-(benzenesulfonyl)carbamoyl-γ-aminopropyl] and 9a-N-[N’-(β-cyanoethyl)-n’-(benzenesulfonyl)carbamoyl-γ-aminopropyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-O-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A WO2004043984 More
- N”-substituted 9a-N-(N’-carbamoyl-γ-aminopropyl), 9a-N-(N’-thiocarbamoyl-γ-aminopropyl), 9a-N-[N’-(β-cyanoethyl)-N’-carbamoyl-γ-aminopropyl] and 9a-N-[N’-(β-cyanoethyl)-N’-thiocarbamoyl-γ-aminopropyl] derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerithromycin A and 5-O-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A WO2004052904 More
- Novel nonsteroidal anti-inflammatory substances, compositions and methods for their use WO2004005309 More
- Novel compounds, compositions as prodrug carriers for steroid/nonsteroid anti-inflammatory, antineoplastic and antiviral active molecules WO2004005313 More
- Novel 14 and 15 membered-ring compounds WO2004101586 More
- Novel 14 and 15 membered ring compounds WO2004101588 More
- New compounds, compositions and methods for treatment of inflammatory diseases and conditions WO2004005310 More
- New 3-decladinosyl derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromicin A 9a,11-cyclic carbamates WO2004029067 More
- New 3-decladinosyl 9a-N-carbamoyl and 9a-N-thiocarbamoyl derivatives of 9-deoxo-9-dihydro-9a-aza-9a homoeritromycin A WO2004101591 More
- Macrolides substituted at the 4″-position WO2004101585 More
- Macrolide conjugates with antiinflammatory activity WO2004094449 More
- Derivatives of 1-thiadibenzoazulenes and their biological activity WO2004078763 More
2003
- Thienodibenzoazulene compounds as tumor necrosis factor inhibitors and their preparation, pharmaceutical compositions and use in the treatment of inflammation US20030153750 More
- 2-Tia-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03084962 More
- 1-Thia-3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03099827 More
- 1-Oxa-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03097649 More
- 1-Oxa-3-aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03084964 More
- 1-Aza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03097648 More
- 1,3-Diaza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03099823 More
- 1,2-Diaza-dibenzoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03099822 More
- 1- or 3-Thia benzonaphthoazulenes as inhibitors of tumor necrosis factor production and intermediates for the preparation thereof WO03084961 More
2002
- Azithromycin for treatment of noninfective inflammatory diseases More
- Conjugates of immune cell specific macrolide compounds with anti-inflammatory compounds for improved cellular targeting of anti-inflammatory therapy WO02055531 More
- 9a-N-[N’-(phenylsulfonyl)carbamoyl]-derivatives of 9-deoxo-9-dihydro-9a-aza-9a-homoerythromycin A and of 5-O-desosaminyl-9-deoxo-9-dihydro-9a-aza-9a-homoerithronolide A WO02068438 More
- Macrolides WO0232917 More
2001
- Thienodibenzoazulene compounds as tumor necrosis factor inhibitors WO0187890 More